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The efficacy and safety of MR-HIFU and US-HIFU in treating uterine fibroids with the volume <300 cm3: a meta-analysis.
- Source :
-
International Journal of Hyperthermia . 2021, Vol. 38 Issue 1, p1126-1132. 7p. - Publication Year :
- 2021
-
Abstract
- High-intensity focused ultrasound (HIFU) is a promising and non-invasive therapy for symptomatic uterine fibroids. Currently, the main image-guided methods for HIFU include magnetic resonance-guided (MR-HIFU) and ultrasound-guided (US-HIFU). However, there are few comparative studies on the therapeutic efficacy and safety of MR-HIFU and US-HIFU in treating symptomatic uterine fibroids with a volume <300 cm3. We performed this meta-analysis to evaluate the efficacy and safety of MR-HIFU and US-HIFU in treating symptomatic uterine fibroids with a volume <300 cm3. We searched relevant literature in PubMed, EMBASE, Cochrane Library CNKI from inception until 2021. The mean value, the proportion, and their 95% confidence intervals (CIs) were measured by random-effects models. Publication bias was assessed using funnel plots. 48 studies met our inclusion criteria—28 describing MR-HIFU and 20 describing US-HIFU. The mean non-perfused volume rate (NPVR) was 81.07% in the US-HIFU group and 58.92% in the MR-HIFU group, respectively. The mean volume reduction rates at month-3, month-6, and month-12 were 42.42, 58.72, and 65.55% in the US-HIFU group, while 34.79, 37.39, and 36.44% in the MR-HIFU group. The incidence of post-operative abdominal pain and abnormal vaginal discharge in the US-HIFU group was lower than that of MRI-HIFU. However, post-operative skin burn and sciatic nerve pain were more common in the US-HIFU group compared with MRI-HIFU. The one-year reintervention rate after MR-HIFU was 13.4%, which was higher than 5.2% in the US-HIFU group. US-HIFU may show better efficiency and safety than MR-HIFU in treating symptomatic fibroids with a volume <300 cm3. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02656736
- Volume :
- 38
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- International Journal of Hyperthermia
- Publication Type :
- Academic Journal
- Accession number :
- 154261288
- Full Text :
- https://doi.org/10.1080/02656736.2021.1954245