Jak zvýšit efektivitu programů EHK u hormonů.

Objective: Demonstration of low effectivity in programs EQA for hormone in serum and possibilities for its improvement. Method: Minireview about possibilities of improving reference values for assessment of results, for bias determination and for kind of control materials. Results: Missing standardization, harmonization and metrological traceability are resolved by using average values from individual methods like EQA reference target for assessment of laboratory results. There are frequently subdivided according to platforms and "generations" of the same producers. It leads to minimalization of validity in quality assessment and paradoxically to falsely high successfulness of labs in EQA. We briefly introduce possibilities of improvement of validity and effectiveness of hormone measurement by different ways. From mathematical recalibration to standardization by means of mass spectrometry methods. Conclusion: Commutability of control materials and creating the reference systems based on mass spectrometry can resolve poor situation and increase effectiveness of ERQA programs for hormone. [ABSTRACT FROM AUTHOR]