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The roles of T cells in obese adipose tissue inflammation.
- Source :
-
Adipocyte . Dec 2021, Vol. 10 Issue 1, p435-445. 11p. - Publication Year :
- 2021
-
Abstract
- Adipose tissue inflammation in obese patients can cause a series of metabolic diseases. There are a variety of immune cells in adipose tissue, and studies have shown that T cells are associated with adipose tissue inflammation. This review aims to describe the current understanding of the relationship between T cells and adipose tissue inflammation, with a focus on regulation by T cell subtypes. Studies have shown that Th1, Th17 and CD8+ T cells, which are important T cell subsets, can promote the development of adipose tissue inflammation, whereas Treg cells protect against inflammation, suggesting that targeting the mechanism by which T cell subtypes regulate adipose tissue inflammation is a potential therapeutic strategy for treating obesity. T cells play important roles in regulating obesity-associated adipose tissue inflammation, thus providing new research directions for the treatment of obesity. More studies are needed to clarify how T cell subtypes regulate adipose tissue inflammation to identify new treatments for obesity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *T cells
*ADIPOSE tissues
*FAT cells
*REGULATORY T cells
*INFLAMMATION
Subjects
Details
- Language :
- English
- ISSN :
- 21623945
- Volume :
- 10
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Adipocyte
- Publication Type :
- Academic Journal
- Accession number :
- 154292450
- Full Text :
- https://doi.org/10.1080/21623945.2021.1965314