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Sulfo-click chemistry with 18F-labeled thio acids.
- Source :
-
Chemical Communications . 1/28/2019, Vol. 55 Issue 9, p1310-1313. 4p. - Publication Year :
- 2019
-
Abstract
- The first application of sulfo-click chemistry with 18F-labeled thio acids is described. The simple one-pot/three-component reaction proceeded rapidly within 30 min using mild reaction conditions to give various 18F-labeled small molecule N-acylsulfonamides in radiochemical conversions of 38–99%, and radiolabeled peptides in 20–25% isolated and decay-corrected radiochemical yields. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SMALL molecules
*ACIDS
*CLICK chemistry
*PEPTIDES
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 55
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 154431998
- Full Text :
- https://doi.org/10.1039/c8cc08717b