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Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection.

Authors :
de Almeida, Breno Lima
Giovanetti, Marta
Oliveira, João Vitor
Carvalho, Tereza Cristina Xavier
Figueiredo, Eduardo Manoel
Pellegrini, Rosana
Calcagno, Juan Ignacio
Carneiro, Marcia Weber
de Oliveira, Juliana M.G.C.
Faiçal, Adriana Virgínia Barros
Agra, Iluska Andrade
Salles, Cristina
Leão, Emília Katiane Embiruçu de Araújo
Lucena, Rita
Acosta, Angelina X.
Alcantara, Luiz Carlos Junior
de Siqueira, Isadora Cristina
Source :
International Journal of Infectious Diseases. Jan2022, Vol. 114, p128-131. 4p.
Publication Year :
2022

Abstract

• This series details 14 asymptomatic normocephalic newborns with confirmed congenital Zika infection. • All newborns presented Zika virus (ZIKV) positivity by reverse transcriptase polymerase chain reaction. • This series corroborates the neonatal screening for ZIKV in endemic areas. Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic analysis revealed that this isolate belonged to the Asian genotype, and clustered closely with other sequences previously isolated in north-east and northern regions of Brazil. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
12019712
Volume :
114
Database :
Academic Search Index
Journal :
International Journal of Infectious Diseases
Publication Type :
Academic Journal
Accession number :
154436108
Full Text :
https://doi.org/10.1016/j.ijid.2021.10.051