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Dynamics of antibody response to BNT162b2 mRNA COVID-19 vaccine after 6 months.
- Source :
-
Journal of Travel Medicine . Dec2021, Vol. 28 Issue 8, p1-3. 3p. - Publication Year :
- 2021
-
Abstract
- Keywords: Pfizer COVID-19 vaccine; SARS-CoV-2; S-RBD-specific; immunoglobulins; seroconversion; decreasing immunity; neutralizing antibodies EN Pfizer COVID-19 vaccine SARS-CoV-2 S-RBD-specific immunoglobulins seroconversion decreasing immunity neutralizing antibodies 1 3 3 01/05/22 20211201 NES 211201 Research letter Emerging evidence is offering significant insights into the effectiveness and safety of the vaccination against the Coronavirus Disease 2019 (COVID-19), but another crucial aspect of the current global vaccination campaign is the time trend of the antibody response to COVID-19 vaccines over a longer period and the resulting duration of the protection offered.1 Here, we present data on the dynamics of antibodies that bind SARS-CoV-2 spike (S) protein receptor binding domain (RBD) - the most critical target for SARS-CoV-2-specific antibodies within the S1 sub-unit2 - after 6 months from the administration with BNT162b2 vaccine. Pfizer COVID-19 vaccine, SARS-CoV-2, S-RBD-specific, immunoglobulins, seroconversion, decreasing immunity, neutralizing antibodies Complete methods of the VASCO project have been presented elsewhere.3 In this survey, HCWs who were administered the two-dose BNT162b2 mRNA vaccine 21 days apart between December 2020 and January 2021 were invited to undertake a quantitative serology test for the research of SARS-CoV-2 S-RBD-specific immunoglobulins G (IgG). [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 11951982
- Volume :
- 28
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Journal of Travel Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 154458135
- Full Text :
- https://doi.org/10.1093/jtm/taab173