癫痫患者睡眠障碍特点及失眠症状与认知功能､焦虑抑郁的关系研究.

To explore the sleep disorders characteristics in patients with epilepsy, and to analyze the relationship between insomnia symptoms and cognitive function, anxiety and depression. A total of 120 patients with epilepsy who were admitted to our hospital from February 2018 to June 2020 were included as the research subjects (epilepsy group), and they were divided into insomnia group (ISI score ≥ 15 scores) and non-insomnia group (ISI score < 15 scores) according to the total score of insomnia severity index scale (ISI). Another 50 healthy subjects were selected as the healthy control group, the characteristics of sleep disorders in epilepsy patients were discussed, and the relationship between insomnia symptoms and cognitive function and anxiety and depression was analyzed. The Pittsburgh Sleep Quality Scale (PSQI) score (4.45±1.26) scores, ISI score (12.35±5.63) scores and Epworth Sleepiness Scale (ESS) score (6.32±3.54) scores in epilepsy group were higher than those in healthy control group (3.11±1.03) scores, (9.62 ±5.14) scores and (5.12 ±3.06) scores, the differences were statistically significant (P<0.05). The patients with epilepsy with insomnia accounted for 19.17% (23/120), and without insomnia accounted for 80.83% (97/120) respectively. There were significant differences in the disease course, ISI score and seizure type between the epilepsy with insomnia group and without insomnia group (P＜ 0.05). The Montreal cognitive assessment scale (MoCA) total score in epilepsy with insomnia group was lower than that in the without insomnia group, Beck depression inventory Edition 2 (BDI-Ⅱ) score, Beck anxiety inventory (BAI) score were higher than those in the without insomnia group, the differences were statistically significant (P＜0.05). Pearson correlation analysis showed that the total ISI score of epilepsy patients was negatively correlated with the total MOCA score (P＜0.05), and the BDI-Ⅱ score, BAI score were positively correlated (P＜0.05). Most patients with epilepsy have sleep disorder, and cognitive function, anxiety and depression symptoms are closely related to insomnia symptoms. [ABSTRACT FROM AUTHOR]