Worsening of COVID-19 after chemotherapy in patients considered to have recovered from a SARS-CoV-2 infection.

In another study, no reactivation was documented following chemotherapy in patients previously infected with SARS-CoV-2, but all patients had negative SARS-CoV-2 PCR on NPS and positive SARS-CoV-2 serology before receiving chemotherapy [[11]]. Given the increased risk of infection after chemotherapy, hematological societies have proposed postponing chemotherapy, when feasible, during the COVID-19 pandemic [[1]], despite initial studies showing no increase in the incidence of COVID-19 among hematological patients [[2]]. It is noteworthy that all three patients had negative serology for SARS-CoV-2 more than one month after their first positive PCR for SARS-CoV-2, suggesting that these patients were not able to develop a humoral immune response against SARS-CoV-2. [Extracted from the article]