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RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes.

Authors :
Hui Ma
Tao Li
Xuefeng Xie
Long Jiang
Jingwei Ye
Chenjia Gong
Hanwei Jiang
Suixing Fan
Huan Zhang
Baolu Shi
Beibei Zhang
Xiaohua Jiang
Yang Li
Jianteng Zhou
Jianze Xu
Xingxia Zhang
Xiaoning Hou
Hao Yin
Yuanwei Zhang
Qinghua Shi
Source :
Science Advances. 1/14/2022, Vol. 8 Issue 2, p1-13. 13p.
Publication Year :
2022

Abstract

The article presents RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes. Topic discussed include Faithful segregation of X and Y chromosomes requires meiotic recombination to form a crossover between them in the pseudo autosomal region (PAR); and double-strand breaks (DSBs) than crossovers, one crossover must be formed from the one or two DSBs in PARs, implying the existence of a sex chromosome–specific recombination mechanism.

Details

Language :
English
ISSN :
23752548
Volume :
8
Issue :
2
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
154639489
Full Text :
https://doi.org/10.1126/sciadv.abk1789