Acute invasive fungal sinusitis: Epidemiology and outcomes in the United States.

During hospitalization for AIFS, diagnoses included immunocompromised state in 67.7% and diabetes/long term insulin use in 55.8%. We could not definitively exclude patients who had pulmonary or other fungal infections whose diagnoses were coded as unspecified or other mycoses, and who during the same hospitalization also had sinus surgery for indications other than AIFS, including chronic invasive fungal sinusitis (CIFS). Keywords: COVID-19; invasive fungal sinusitis; mucormycosis EN COVID-19 invasive fungal sinusitis mucormycosis 233 236 4 01/27/22 20220201 NES 220201 INTRODUCTION Acute invasive fungal sinusitis (AIFS) is a rare and often fatal disease caused by aggressive fungal invasion in the nose and paranasal sinuses, with subsequent thrombosis and progressive tissue necrosis capable of spreading to the orbits and brain over hours. [Extracted from the article]