Peutz-Jeghers Syndrome Presented as Jejunojejunal Intussusception.

Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder characterized by intestinal hamartomatous polyps in association with skin and mucosal macular melanin deposition. There is a lifetime chance of 93% of cancers when all cancers are combined and the incidence of the disease is variable between 1 in 8300 and 1 in 280,000 live births (Daniell et al., Familial Cancer 17(3):421-427, 2018). Here, we present a 14-year-old Indian boy presenting to surgical emergency with intestinal obstruction secondary to jejunojejunal intussusception for which resection and anastomosis were done. Post-operative histopathological examination showed a single polyp leading to intussusception. He classically showed mucocutaneous pigmentation on general examination. Early identification of Peutz-Jeghers syndrome on a routine visit to healthcare can decrease complications like intestinal obstruction and help in starting early surveillance for cancers. [ABSTRACT FROM AUTHOR]