Back to Search
Start Over
Acute kidney injury in premature and low birth weight neonates: a systematic review and meta-analysis.
- Source :
-
Pediatric Nephrology . Feb2022, Vol. 37 Issue 2, p275-287. 13p. 1 Diagram, 1 Chart, 5 Graphs. - Publication Year :
- 2022
-
Abstract
- Background: Acute kidney injury (AKI) is common and it is associated with poor clinical outcomes in premature and low birth weight neonates. This systematic review and meta-analysis was performed to summarize the literature and evaluate the prevalence, risk factors, and mortality of premature and low birth weight neonates with AKI. Methods: A systematic search in PubMed, Embase, and the Cochrane Library was performed. Studies on the prevalence, risk factors, diagnosis, and outcomes of acute kidney injury in preterm neonates and neonates with low birth weight were included and analyzed. Results: Fifty articles of 10,744 patients were included in this study. The overall rate of AKI from the pooled results of all patients was 25% (95% CI 20–30%) with heterogeneity among studies (I2 = 97%; P < 0.01). Patients with AKI had significantly higher rate of mortality than patients without AKI (odds ratio (OR) = 7.13; 95% CI 5.91–8.60; P < 0.01). Conclusions: AKI was prevalent and was associated with high mortality rate among preterm and low birth weight neonates. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ONLINE information services
*PREMATURE infant diseases
*META-analysis
*MEDICAL information storage & retrieval systems
*MEDICAL databases
*INFORMATION storage & retrieval systems
*CONFIDENCE intervals
*SYSTEMATIC reviews
*LOW birth weight
*RISK assessment
*DESCRIPTIVE statistics
*INFANT mortality
*MEDLINE
*ODDS ratio
*ACUTE kidney failure
*DISEASE risk factors
*CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 0931041X
- Volume :
- 37
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Pediatric Nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 155078878
- Full Text :
- https://doi.org/10.1007/s00467-021-05251-0