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The Utility of Gastrointestinal Endoscopic Examination Versus Positron Emission Tomography–Computed Tomography in the Detection of Second Primary Lesions in Korean Patients With Head and Neck Cancer.
- Source :
-
ENT: Ear, Nose & Throat Journal . Feb2022, Vol. 101 Issue 2, pNP50-NP57. 8p. - Publication Year :
- 2022
-
Abstract
- Objective: Head and neck cancer often accompany a synchronous secondary primary lesion in the digestive tract. The aim of this study was to compare detection rates between positron emission tomography–computed tomography (PET-CT) and esophagogastroduodenoscopy (G-fiber) or colonoscopy (C-fiber) in the initial staging and to analyze risk factors for premalignant, malignant, and total synchronous secondary primary lesions. Methods: A total of 739 patients with head and neck cancer who underwent PET-CT, G-fiber, or C-fiber were analyzed retrospectively. Results: Positron emission tomography–CT did not definitely detect any premalignant synchronous secondary primary lesions (0 [0%] of 739) but definitely detected 10 malignant synchronous secondary primary lesions (10 [1.35%] of 739). Esophagogastroduodenoscopy or C-fiber detected all 20 premalignant synchronous secondary primary lesions (20 [2.71%] of 739) and all 37 malignant synchronous secondary primary lesions (37 [5.00%] of 739). The patients with nasopharynx cancer tended to have premalignant synchronous secondary primary lesions (odds ratio [OR]: 3.793; 95% CI: 1.414-10.171; P =.008). Those with distant metastasis tended to have premalignant (OR: 4.743; 95% CI: 1.508-14.916; P =.009), malignant (OR: 3.803; 95% CI: 1.486-9.731; P =.005), and total synchronous secondary primary lesions (OR: 2.753; 95% CI: 1.159-6.538; P =.022). Conclusions: Premalignant or malignant synchronous secondary primary lesions that were not definitely detected by PET-CT could be found in the endoscopic examination. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NASOPHARYNX cancer
*COLONOSCOPY
*CONFIDENCE intervals
*HEAD & neck cancer
*DIGESTIVE system endoscopic surgery
*POSITRON emission tomography computed tomography
*RETROSPECTIVE studies
*METASTASIS
*TUMOR classification
*RISK assessment
*SECONDARY primary cancer
*DESCRIPTIVE statistics
*ENDOSCOPIC gastrointestinal surgery
*ODDS ratio
*PRECANCEROUS conditions
Subjects
Details
- Language :
- English
- ISSN :
- 01455613
- Volume :
- 101
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- ENT: Ear, Nose & Throat Journal
- Publication Type :
- Academic Journal
- Accession number :
- 155214188
- Full Text :
- https://doi.org/10.1177/0145561320940089