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Consumption of Supplementary Inulin Modulates Milk Microbiota and Metabolites in Dairy Cows with Subclinical Mastitis.

Authors :
Yue Wang
Xuemei Nan
Yiguang Zhao
Linshu Jiang
Hui Wang
Fan Zhang
Dengke Hua
Jun Liu
Junhu Yao
Liang Yang
Benhai Xiong
Source :
Applied & Environmental Microbiology. Feb2022, Vol. 88 Issue 4, p1-21. 21p.
Publication Year :
2022

Abstract

The milk microbiota and mediated metabolites directly affect the health of the udder in dairy cows. Inulin, a dietary prebiotic, can modulate the profile of gastrointestinal microbiota. However, whether the inulin intake affects the milk microbial population and metabolites remains unknown. In this study, 40 subclinical mastitis (SCM) cows were randomly divided into 5 groups. Five inulin addition doses, 0, 100, 200, 300, and 400 g/day per cow, based on the same basal diet, were supplemented. The experiments lasted for 8 weeks. The results showed lower relative abundance of mastitis-causing and proinflammation microbes in milk (i.e., Escherichia-Shigella, Pseudomonas, Rhodococcus, Burkholderia-Caballeronia-Paraburkholderia, etc.) and higher abundances of probiotics and commensal bacteria, such as Lactobacillus, Bifidobacterium, etc., in the cows fed 300 g/day inulin compared to that in the control group. Meanwhile, the levels of arachidonic acid proinflammatory mediators (leukotriene E3, 20-carboxy-leukotriene B4, and 12-Oxoc-LTB3) and phospholipid metabolites were reduced, and the levels of compounds with antibacterial and anti-inflammatory potential (prostaglandin A1, 8-iso-15-keto-prostaglandin E2 [PGE2], etc.) and participating energy metabolism (citric acid, L-carnitine, etc.) were elevated. These data suggested that inulin intake might modulate the microflora and metabolite level in extraintestinal tissue, such as mammary gland, which provided an alternative for the regulation and mitigation of SCM. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00992240
Volume :
88
Issue :
4
Database :
Academic Search Index
Journal :
Applied & Environmental Microbiology
Publication Type :
Academic Journal
Accession number :
155422588
Full Text :
https://doi.org/10.1128/aem.02059-21