Solvent-free mechanochemical synthesis of bisthioglycolic acid derivatives: an efficient and versatile strategy for carbon–sulfur bond formation.

An eco-friendly, easily achievable and efficient strategy has been explored to synthesize functionalized bisthioglycolic acids using a variety of aldehydes and thioglycolic acid. The employed protocol is solvent free and provides the desirable products in excellent yields (90–99%) with atom economy. Besides, cost effectiveness, short reaction times and milder reaction conditions are among other captivating benefits of the reported methodology. [ABSTRACT FROM AUTHOR]