Unmet needs in current clinical practice for insulinoma: Lessons from nationwide studies in Japan.

The relatively low proportion of patients who actually underwent surgery, postoperative diabetes mellitus, and residual hypoglycemia have been found as clinical issues. Unmet clinical needs for the management of insulinoma include a low proportion of patients having surgical treatment, postoperative diabetes mellitus, and residual hypoglycemia. However, it is noteworthy that the survey also included 69 patients classified as "unknown" with regard to this factor, i.e., patients who had no information or answers on malignancy in their questionnaire; of them only 30 patients (43.5%) underwent pancreatectomy. [Extracted from the article]