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Chiral pool approach to the total synthesis of phomonol.

Authors :
Dada, Ravikrishna
Yaragorla, Srinivasarao
Source :
Synthetic Communications. 2022, Vol. 52 Issue 3, p445-450. 6p. 5 Diagrams.
Publication Year :
2022

Abstract

We report a stereoselective total synthesis of a natural product, phomonol, from readily available D-aspartic acid. The key steps include Wittig olefination, Sharpless asymmetric dihydroxylation, Grignard addition, diastereoselective reductive etherification and Wacker oxidation. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*NATURAL products
*ETHERIFICATION

Details

Language :
English
ISSN :
00397911
Volume :
52
Issue :
3
Database :
Academic Search Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
155892710
Full Text :
https://doi.org/10.1080/00397911.2022.2031223
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