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Chiral pool approach to the total synthesis of phomonol.
- Source :
-
Synthetic Communications . 2022, Vol. 52 Issue 3, p445-450. 6p. 5 Diagrams. - Publication Year :
- 2022
-
Abstract
- We report a stereoselective total synthesis of a natural product, phomonol, from readily available D-aspartic acid. The key steps include Wittig olefination, Sharpless asymmetric dihydroxylation, Grignard addition, diastereoselective reductive etherification and Wacker oxidation. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NATURAL products
*ETHERIFICATION
Subjects
Details
- Language :
- English
- ISSN :
- 00397911
- Volume :
- 52
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Synthetic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 155892710
- Full Text :
- https://doi.org/10.1080/00397911.2022.2031223