Personalized Medicine in the Field of Inflammatory Skin Disorders.

Sobolev et al. found a differential expression of six estrogen-controlled genes (HMOX1, KRT19, LDHA, HSPD1, MAPK1, and CA2) in the skin of female patients with psoriasis compared to male patients with psoriasis and concluded that these proteins may be involved in the defense of skin cells against inflammation damage. Inflammatory skin diseases occur after the onset of abnormal immune cell responses and the activation of various immune signaling pathways in the skin [[1]]. In the treatment of atopic dermatitis, important advances are being made, and Janus kinase inhibitors (JAK) represent new treatment options. Personalized medicine stratifies patients based on molecular markers and allows the identification of the best possible solution for the patient. [Extracted from the article]