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Targeting solute carriers to modulate receptor–ligand interactions.
- Source :
-
Trends in Pharmacological Sciences . May2022, Vol. 43 Issue 5, p358-361. 4p. - Publication Year :
- 2022
-
Abstract
- Solute carrier transporters (SLCs) limit receptor activation via uptake of extracellular ligands. Novel concepts are emerging that describe the modulation of intracellular and plasma membrane receptors by ligand influx and efflux via SLCs, respectively. Here, we evaluate recent insights and provide an outlook for developing potential therapeutic strategies. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CELL membranes
*LIGANDS (Biochemistry)
Subjects
Details
- Language :
- English
- ISSN :
- 01656147
- Volume :
- 43
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Trends in Pharmacological Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 156254834
- Full Text :
- https://doi.org/10.1016/j.tips.2022.02.004