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血液细胞分析仪红细胞碎片参数检测性能评价.
- Source :
-
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao . 2022, Vol. 43 Issue 4, p93-98. 6p. - Publication Year :
- 2022
-
Abstract
- Objective Fragmented red blood cells (FRC) is a new detection parameter provided by the automatic blood cell analyzer, which is closely related to thrombotic microangiopaemia and other diseases. This study is aimed at evaluating the detection performance of automatic hematology analyzer for RBC fragments. Methods The performance of SYSMEX XN series automatic blood cell analyzer was evaluated by carrying contamination rate, precision, linearity, accuracy, sensitivity, specificity and other indicators. All data were analyzed by SPSS 19.0 software. Results The contamination rate of red blood cell fragments detected by SYSMEX XN series automatic hematology analyzer was 0.11%. Intra-batch precision: coefficient of variation (CV) at each experimental concentration were 8.75% (42.15×109/L), 6.38% (83.42×109/L), 4.57% (228.74×109/L), 5.31% (796.89×109/L). Linear verification: the linear regression equation was Y = 1.000 1X + 9.328 8, and the correlation coefficient is r = 0.9936., and the correlation coefficient is R =0.993 6; Correctness verification: compared with manual microscopy, the was no statistically significant difference(P>0.05), the correlation coefficient, sensitivity and specificity were r = 0.82, 92% and 82% respectively. Conclusion SYSMEX XN series automatic blood cell analyzer is quick and easy to operate in detecting red blood cell fragments, with low contamination rate, fair precision and satisfactory linear range. Compared with manual microscopy, it has better correlation, higher specificity and sensitivity. Blood cell analyzer can be used as a rapid screening method for fragments of peripheral blood red blood cells, but the precision of its detection still needs to be further improved, and due to the limitations of the method, positive specimens need to be confirmed under a microscope. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Chinese
- ISSN :
- 2095610X
- Volume :
- 43
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Kunming Medical University / Kunming Yike Daxue Xuebao
- Publication Type :
- Academic Journal
- Accession number :
- 156383723
- Full Text :
- https://doi.org/10.12259/j.issn.2095-610X.S20220415