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Emerging role of m6A modification in cardiovascular diseases.
- Source :
-
Cell Biology International . May2022, Vol. 46 Issue 5, p711-722. 12p. - Publication Year :
- 2022
-
Abstract
- Cardiovascular diseases (CVDs) contribute to the leading cause of death worldwide. Despite significant improvements in CVDs diagnosis and treatment, a continued effort to explore novel therapeutic strategies is urgently need. N6‐methyladenosine (m6A) RNA methylation, well known as the most prevalent type of RNA modifications, involved in RNA stability, nuclear exports, translation, and decoy, plays a crucial role in the pathogenesis of a variety of diseases, including CVDs, cancer, and drug resistance. Here, our article summarizes cellular functions of m6A modulators and recent research progress concerning the functions and mechanisms of m6A methylation in CVDs, in hope of providing references for exploring novel therapeutic approaches and potential biomarkers in the treatment of CVDs. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10656995
- Volume :
- 46
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Cell Biology International
- Publication Type :
- Academic Journal
- Accession number :
- 156467320
- Full Text :
- https://doi.org/10.1002/cbin.11773