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Emerging role of m6A modification in cardiovascular diseases.

Authors :
Peng, Liming
Long, Tianyi
Li, Fei
Xie, Qiying
Source :
Cell Biology International. May2022, Vol. 46 Issue 5, p711-722. 12p.
Publication Year :
2022

Abstract

Cardiovascular diseases (CVDs) contribute to the leading cause of death worldwide. Despite significant improvements in CVDs diagnosis and treatment, a continued effort to explore novel therapeutic strategies is urgently need. N6‐methyladenosine (m6A) RNA methylation, well known as the most prevalent type of RNA modifications, involved in RNA stability, nuclear exports, translation, and decoy, plays a crucial role in the pathogenesis of a variety of diseases, including CVDs, cancer, and drug resistance. Here, our article summarizes cellular functions of m6A modulators and recent research progress concerning the functions and mechanisms of m6A methylation in CVDs, in hope of providing references for exploring novel therapeutic approaches and potential biomarkers in the treatment of CVDs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10656995
Volume :
46
Issue :
5
Database :
Academic Search Index
Journal :
Cell Biology International
Publication Type :
Academic Journal
Accession number :
156467320
Full Text :
https://doi.org/10.1002/cbin.11773