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Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.

Authors :
Bronge, Mattias
Högelin, Klara Asplund
Thomas, Olivia G.
Ruhrmann, Sabrina
Carvalho-Queiroz, Claudia
Nilsson, Ola B.
Kaiser, Andreas
Zeitelhofer, Manuel
Holmgren, Erik
Linnerbauer, Mathias
Adzemovic, Milena Z.
Hellström, Cecilia
Jelcic, Ivan
Hao Liu
Nilsson, Peter
Hillert, Jan
Brundin, Lou
Fink, Katharina
Kockum, Ingrid
Tengvall, Katarina
Source :
Science Advances. 4/27/2022, Vol. 8 Issue 17, p1-18. 31p.
Publication Year :
2022

Abstract

The article presents a study which explores the identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis. It mentions the systematic efforts to date in the search for Multiple sclerosis (MS) autoantigens, demonstrates the heterogeneity of autoreactive profiles, and highlights promising targets for future diagnostic tools and immunomodulatory therapies in MS.

Details

Language :
English
ISSN :
23752548
Volume :
8
Issue :
17
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
156573520
Full Text :
https://doi.org/10.1126/sciadv.abn1823