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Microneedling with topical vitamin C versus microneedling with topical insulin in the treatment of atrophic post‐acne scars: A split‐face study.
- Source :
-
Dermatologic Therapy . May2022, Vol. 35 Issue 5, p1-6. 6p. - Publication Year :
- 2022
-
Abstract
- Post acne scars following sebaceous injury and abnormal wound healing during the course of acne is a prevalent and challenging to treat condition To evaluate microneedling by dermapen with topical vitamin C versus microneedling with topical insulin in treating atrophic post‐acne scars. A split‐face comparative study included 30 subjects with atrophic post‐acne scars. Human insulin was topically applied to the left side of the face and on the right side, vitamin C serum was applied. Scars were assessed via the Acne Scar Assessment Scale (ASAS) and Scar quartile grading scale (SQGS). After 1 month of 4 treatments, a statistically significant mean improvement in ASAS value was reported on both split sides of the face (2.13 and 1.83) compared to baseline (3.03 and 2.93) (p = 0.005; p = 0.001 respectively). When compared to baseline, the mean ASAS value improved significantly with a slight more improvement on the vitamin c treated side. Topical insulin and vitamin c combined with microneedling, may both achieve comparable significant improvement for treating post acne scars. Insulin can be a promising novel anti‐scarring therapy pending larger controlled studies to verify its efficacy. [ABSTRACT FROM AUTHOR]
- Subjects :
- *VITAMIN C
*INSULIN therapy
*WOUND healing
*SCARS
Subjects
Details
- Language :
- English
- ISSN :
- 13960296
- Volume :
- 35
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Dermatologic Therapy
- Publication Type :
- Academic Journal
- Accession number :
- 156712340
- Full Text :
- https://doi.org/10.1111/dth.15376