Synthesis of Isoquinoline-1,3(2 H ,4 H)-diones by Visible-Light-Mediated Cyclization of Acryloylbenzamides with Alkylboronic Acids, Arylsulfonyl Hydrazides and Oxime Esters.

An efficient visible-light-mediated tandem reaction of acryl-oylbenzamides with alkylboronic acids, arylsulfonyl hydrazides and oxime esters has been developed. The reaction proceeds via radical addition and cyclization to give various isoquinoline-1,3(2 H ,4 H)-diones in satisfactory yields under mild conditions, which provides a good opportunity to discover new meaningful bioactive compounds. [ABSTRACT FROM AUTHOR]