Back Cover: Glutathione Depletion‐Induced Activation of Dimersomes for Potentiating the Ferroptosis and Immunotherapy of "Cold" Tumor (Angew. Chem. Int. Ed. 22/2022).

Keywords: Cancer Immunotherapy; Drug Delivery; Ferroptosis; GSH Depletion; Vesicles EN Cancer Immunotherapy Drug Delivery Ferroptosis GSH Depletion Vesicles 1 1 1 05/18/22 20220523 NES 220523 B Glutathione b (GSH) is abundant in "cold" tumors and adversely affects ferroptosis therapy and immune response. In their Research Article (e202202843), Minjie Sun and co-workers developed cinnamaldehyde-dimer-based vesicles (CDC dimersomes) capable of depleting intracellular GSH via Michael addition to potentiate the ferroptosis and immunotherapy of breast cancer by turning the "cold" tumor into a "hot" tumor. Back Cover: Glutathione Depletion-Induced Activation of Dimersomes for Potentiating the Ferroptosis and Immunotherapy of "Cold" Tumor (Angew. [Extracted from the article]