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Colorimetric sensing strategy for detection of cysteine, phenol cysteine, and phenol based on synergistic doping of multiple heteroatomsĀ into sponge-like Fe/NPC nanozymes.
- Source :
-
Analytical & Bioanalytical Chemistry . Jun2022, Vol. 414 Issue 14, p4217-4225. 9p. - Publication Year :
- 2022
-
Abstract
- Nanozymes have both the high catalytic activity of natural enzymes and the stability and economy of mimetic enzymes. Research on nanozymes is rapidly emerging, and the continuous development of highly catalytic active nanozymes is of far-reaching significance. This work reports heteroatomic nitrogen (N) and phosphorus (P) double-doped mesoporous carbon structures and metallic Fe coordination generated sponge-like nanozymes (Fe/NPCs) with good peroxidase activity. On this basis, we constructed a highly sensitive colorimetric sensor with cysteine and phenol as simulated analytes using Fe/NPCs nanozymes, and the response limits reached 53.6 nM and 5.4 nM, respectively. Besides, the method has high accuracy in the detection of cysteine and phenol at low concentrations in serum and tap water, which lays a foundation for application in the fields of environmental protection and biosensors. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SYNTHETIC enzymes
*ENZYME stability
*CYSTEINE
*DRINKING water
*CATALYTIC activity
Subjects
Details
- Language :
- English
- ISSN :
- 16182642
- Volume :
- 414
- Issue :
- 14
- Database :
- Academic Search Index
- Journal :
- Analytical & Bioanalytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 157007201
- Full Text :
- https://doi.org/10.1007/s00216-022-04074-8