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Viral Load as a Factor Affecting the Fatality of Patients Suffering from Severe Fever with Thrombocytopenia Syndrome.
- Source :
-
Viruses (1999-4915) . May2022, Vol. 14 Issue 5, p881-881. 11p. - Publication Year :
- 2022
-
Abstract
- The clinical characteristics and the effect of viral RNA loads on fatality in 56 patients with severe fever with thrombocytopenia syndrome (SFTS) were analyzed. The non-survival group (12 patients) demonstrated a significantly higher mean age (77 years) than the survival group (44 patients, 65 years) (p = 0.003). The survival rates were 91.7% and 8.3% in patients with Ct values ≥30 and differed significantly (p = 0.001) in the survival and non-survival groups, respectively. The survival rates were 52.4% and 47.6% in patients with viral copy numbers ≥10,000 and 94.3% and 5.7% in patients with viral copy numbers <10,000 in the survival and non-survival groups, respectively (p = 0.001). In a multivariate analysis, viral copy numbers and initial Acute Psychologic Assessment and Chronic Health Evaluation II (APACHE II) scores were identified as the factors affecting fatality (p = 0.015 and 0.011, respectively). SFTS viral RNA loads can be useful markers for the clinical prediction of mortality and survival. [ABSTRACT FROM AUTHOR]
- Subjects :
- *THROMBOCYTOPENIA
*BIOMARKERS
*SURVIVAL rate
*MULTIVARIATE analysis
*SUFFERING
Subjects
Details
- Language :
- English
- ISSN :
- 19994915
- Volume :
- 14
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Viruses (1999-4915)
- Publication Type :
- Academic Journal
- Accession number :
- 157237725
- Full Text :
- https://doi.org/10.3390/v14050881