Back to Search
Start Over
Regulation of wound healing and fibrosis by galectins.
- Source :
-
Journal of Molecular Medicine . Jun2022, Vol. 100 Issue 6, p861-874. 14p. - Publication Year :
- 2022
-
Abstract
- Galectins are a family of proteins with at least one carbohydrate-recognition domain. Galectins are present in various tissues and organs and participate in different physiological and pathological molecular reactions in vivo. Wound healing is the basic process of traumatic disease recovery. Wound healing involves three overlapping stages: inflammation, proliferation, and remodelling. Furthermore, a comparison of wound healing with the tumour microenvironment revealed that galectin plays a key role in the wound healing process. The current review describes the role of galectin in inflammation, angiogenesis, re-epithelialisation, and fibrous scar formation and evaluates its potential as a therapeutic drug for wounds. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GALECTINS
*WOUND healing
*FIBROSIS
*TUMOR microenvironment
*NEOVASCULARIZATION
Subjects
Details
- Language :
- English
- ISSN :
- 09462716
- Volume :
- 100
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Journal of Molecular Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 157264246
- Full Text :
- https://doi.org/10.1007/s00109-022-02207-1