Secretory phospholipase A2 group XIIBs play potential roles in intestine antibacterial responses in seahorse.

Considering that the intestine is always in close contact with microorganisms and is vulnerable to pathogen invasion (Lawley & Walker, 2013; Li et al., 2015), the highest expression pattern implied that the two seahorse sPLA2-XIIBs might play an important role in intestinal immunity. Keywords: antibacterial response; intestine; seahorse; secretory phospholipase A2 group XIIB EN antibacterial response intestine seahorse secretory phospholipase A2 group XIIB 1059 1063 5 06/10/22 20220701 NES 220701 Aquatic diseases caused by pathogenic bacteria have seriously hindered the development of seahorse aquaculture, which is supposed to bridge the gap between the increasing demand for medicinal markets and decreasing wild seahorse populations (Jiang et al., 2020; Li et al., 2020; Qin et al., 2017). Therefore, the two sPLA2-XIIBs identified in seahorses are homologous to the sPLA2-XIIBs in teleosts. The qPCR results showed that the expression levels of the two sPLA2-XIIB genes in the intestine of the I Vibrio i -infected seahorses were significantly higher than those of healthy seahorses (Figure 3a). [Extracted from the article]