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Interrupting Prolonged Sitting with Intermittent Walking Increases Postprandial Gut Hormone Responses.
- Source :
-
Medicine & Science in Sports & Exercise . Jul2022, Vol. 54 Issue 7, p1183-1189. 7p. - Publication Year :
- 2022
-
Abstract
- Introduction: Continuous exercise can increase postprandial gut hormone such as glucagon-like peptide 1 (GLP-1) and peptide YY (PYY) responses, but it is unknown whether interrupting prolonged sitting with intermittent walking elicits this effect. Method: Ten participants with central overweight/obesity (7 men and 3 postmenopausal women, 51 ± 5 yr; mean ± SD) completed a randomized crossover study in which they consumed breakfast and lunch in the laboratory while either sitting continuously for the entire 5.5-h period (SIT) or the prolonged sitting interrupted every 20 min by walking briskly (6.4 km·h−1) for 2 min (BREAKS). Blood samples were collected at regular intervals to examine postprandial plasma GLP-1, PYY, and glucose-dependent insulinotropic polypeptide concentrations. Adipose tissue samples were collected at baseline and at the end of the trials to examine changes in net dipeptidyl peptidase 4 secretion from primary explants. Results: Mean (95% confidence interval) postprandial GLP-1 and PYY incremental area under curve values were elevated by 26% and 31% in the BREAKS trial versus SIT (8.4 [0.7, 16.1] vs 6.7 [−0.8, 14.2], P = 0.001, and 26.9 [8.1, 45.6] vs 20.4 [5.1, 35.8] nmol·330 min·L−1, P = 0.024, respectively) but without any such effect on glucose-dependent insulinotropic polypeptide (P = 0.076) or net adipose tissue dipeptidyl peptidase 4 secretion (P > 0.05). Conclusions: Interrupting prolonged sitting with regular short bouts of brisk walking increases postprandial GLP-1 and PYY concentrations in healthy middle-age men and women with central adiposity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *OBESITY
*SITTING position
*WALKING
*GASTROINTESTINAL hormones
Subjects
Details
- Language :
- English
- ISSN :
- 01959131
- Volume :
- 54
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Medicine & Science in Sports & Exercise
- Publication Type :
- Academic Journal
- Accession number :
- 157463568
- Full Text :
- https://doi.org/10.1249/MSS.0000000000002903