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Cupric oxide nanoparticles incorporated poly(hydroxybutyrate) nanocomposite for potential biosensing application.
- Source :
-
International Journal of Biological Macromolecules . Jul2022, Vol. 213, p1018-1028. 11p. - Publication Year :
- 2022
-
Abstract
- We report the synthesis of a novel electrochemical biosensor comprising of cupric oxide (CuO) nanoparticles (NPs) mediated poly(hydroxybutyrate) (PHB) composite film with polyvinyl alcohol (PVA) as a binder/template support using the solution casting method for the detection of a biomolecule i.e., ascorbic acid (AA). The specimens were characterized for surface, chemical, mechanical, optical, and electrochemical attributes. The results expressed regular mediation of CuO NPs in the PHB/PVA matrix towards nanobiocomposite formation with enhanced crystallinity, inter-molecular interactions, mechanical, and electrochemical attributes, and decreased hydrophilicity and bandgap, thus being useful in potential optoelectronic devices. The synthesized biocomposite film exhibited a tensile strength of 86.24 ± 4.10 N which might be due to reinforcement/uniform dispersion of the CuO nanofiller in the PHB-based matrix. The PHB/CuO composite, then, deposited on a glassy carbon electrode surface exhibited good electrocatalytic activity towards the AA in the aqueous media even at low analyte concentrations. Such modified electrode surfaces with metal/biopolymer complex could find possible applications in the detection of other bioactive molecules. • We present the synthesis of CuO nanoparticles (NPs) mediation in poly(hydroxybutyrate) (PHB)-based composite. • The nanocomposite films were thermally stable and less hydrophilic as compared to the control. • The nanobiocomposite was deposited on a glassy carbon electrode for biosensing application. • Such modified electrode surfaces may find potential applications in the detection of bioactive molecules. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01418130
- Volume :
- 213
- Database :
- Academic Search Index
- Journal :
- International Journal of Biological Macromolecules
- Publication Type :
- Academic Journal
- Accession number :
- 157522480
- Full Text :
- https://doi.org/10.1016/j.ijbiomac.2022.06.018