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Advances in CD247.
- Source :
-
Scandinavian Journal of Immunology . Jul2022, Vol. 96 Issue 1, p1-11. 11p. - Publication Year :
- 2022
-
Abstract
- CD247, which is also known as CD3ζ, CD3H, CD3Q, CD3Z, IMD25, T3Z and TCRZ, encodes CD3ζ protein, which is expressed primarily in natural killer (NK) and T cells. Since the discovery of the ζ peptide in 1986, it has been continuously investigated. In this paper, we review the composition, molecular mechanisms and regulatory factors of CD247 expression in T cells; and review the autoimmune diseases, tumours and inflammatory diseases associated with CD247, providing a detailed and comprehensive reference for further research on the mechanism of CD247 and related diseases. [ABSTRACT FROM AUTHOR]
- Subjects :
- *T cells
*AUTOIMMUNE diseases
*PEPTIDES
Subjects
Details
- Language :
- English
- ISSN :
- 03009475
- Volume :
- 96
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Scandinavian Journal of Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 157776216
- Full Text :
- https://doi.org/10.1111/sji.13170