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Association of inflammatory bowel disease with suicidal ideation, suicide attempts, and suicide: A systematic review and meta-analysis.
- Source :
-
Journal of Psychosomatic Research . Jul2022, Vol. 158, p110983-110983. 1p. - Publication Year :
- 2022
-
Abstract
- <bold>Objective: </bold>Inflammatory bowel disease (IBD) is associated with psychiatric comorbidities. However, the association between IBD and suicidal ideation or suicide attempts has not been well established. This study aimed to perform a systematic review and meta-analysis to elucidate the relationship between IBD and suicidal ideation, suicide attempts, and suicide.<bold>Methods: </bold>We systematically searched five electronic databases - PubMed, Embase, CENTRAL, Web of Science, and PsycINFO - from their inception to January 28, 2022. Quality assessment, data synthesis, subgroup analyses, sensitivity analyses, and publication bias assessment were performed on the included studies.<bold>Results: </bold>We identified 28 studies with 1,047,755 patients with IBD. The pooled prevalence of suicidal ideation in patients with IBD was 17.3% (95% CI, 9.5%-25.2%). Patients with IBD were associated with an increased risk of suicide attempts (relative risk [RR], 1.39; 95% CI, 1.08-1.79) and suicide deaths (RR, 1.25; 95% CI, 1.09-1.43) than the controls without IBD. Patients with Crohn's disease subtypes, female IBD, pediatric-onset IBD, young adult IBD, and short-duration IBD had a particularly high risk for suicide.<bold>Conclusion: </bold>Patients with IBD had a high prevalence of suicidal ideation and a significantly higher likelihood of suicide attempts and suicide. Caring for patients with IBD, including their mental health needs, may require concerted efforts among gastroenterologists and other healthcare providers. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00223999
- Volume :
- 158
- Database :
- Academic Search Index
- Journal :
- Journal of Psychosomatic Research
- Publication Type :
- Academic Journal
- Accession number :
- 158141402
- Full Text :
- https://doi.org/10.1016/j.jpsychores.2022.110983