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The amino acid sequence of rabbit skeletal muscle glycogenin.
- Source :
-
European Journal of Biochemistry . 10/20/89, Vol. 185 Issue 1, p119-125. 7p. - Publication Year :
- 1989
-
Abstract
- The amino acid sequence of glycogenin from rabbit skeletal muscle has been determined. The N-acetylated protein consists of 332 amino acids and has a molecular mass of 37278 Da. The novel tyrosyl-glucose linkage between glycogenin and glycogen [Smythe, C., Caudwell, F. B., Ferguson, M. & Cohen, P. (1988) EMBO J. 7, 2681 -2686] is shown to occur at a single site, tyrosine-194. Although glycogenin is a UDPaGIc utilising glucosyltransferase that self-glucosylates [Pitcher, J., Smythe, C. & Cohen, P. (1988) Eur. J. Biochem. 176, 391 - 395], following addition by an unknown enzyme of the first glucose to tyrosine-194, it is not homologous to either human glycogen synthase or other UDP-Glc-requiring enzymes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *AMINO acids
*ORGANIC acids
*GLYCOGEN
*PROTEIN analysis
*GLUCOSE
*ENZYMES
Subjects
Details
- Language :
- English
- ISSN :
- 00142956
- Volume :
- 185
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- European Journal of Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 15818998
- Full Text :
- https://doi.org/10.1111/j.1432-1033.1989.tb15090.x