延边地区 2020 年丙型肝炎抗体筛查结果分析.

Objective To investigate the influencing factors for hepatitis C antibody and the preventive effect of hepatitis C in Yanbian Prefecture of China in the recent 7 years. Methods A total of 1184 residents in Yanbian were randomly selected in 2020, peripheral blood samples were collected, and the colloidal gold method was used to detect hepatitis C antibody. The positive rate of hepatitis C antibody in 2020 was compared with the data in 2013. The chi — square test or the Fisher' s exact test was used for comparison of categorical data be-tween groups, and then pairwise comparison was performed. Results The positive rate of hepatitis C antibody in Yanbian residents screened in 2020 was significantly lower than that in 2013 ( 6.42% vs 10.60%, χ² = 11. 212, P = 0. 001). The Fisher' s exact test (2 x C) was per-formed for the positive rate of hepatitis C antibody between different age groups in 2020, and the results showed that there was a significant difference between the 5 age groups (χ² = 29. 478, P <0.001 ). Pairwise comparison after Bonfenoni adjustment showed that there was a significant difference between the ≥ 60 years group and the 50 —59 years group, between the ≥60 years group and the 40 —49 years group, and between the ≥60 years group and the 30 —39 years group (χ² = 11. 268,14. 804, and 9. 293, all P <0.01), while there was no significant difference between the other groups (P >0. 01). The Chinese Korean population had a significantly higher positive rate of antibody than the non — Chinese Korean population (10.45% vs 5.50%, χ² = 7. 236, P = 0. 007 ) . As for the farmers, the positive rate of hepatitis C antibody in 2020 was significantly lower than that in 2013 (7. 16% vs 19.74%a, χ² = 36. 604, P <0. 001 ). The positive rate of hepatitis C antibody in rural areas was significantly higher than that in urban areas (7.33% vs 4.26%, χ² = 3. 882, P =0.049) . Conclusion The positive rate of hepatitis C antibody is mainly associated with age, nationality, occupation, and region. There is a reduction in the positive rate of hepatitis C antibody in Yanbian in the recent 7 years, suggesting that Yanbian Prefecture has achieved a marked effect in the prevention and treatment of hepatitis C. [ABSTRACT FROM AUTHOR]