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The reaction of trout hemoglobins with isocyanides.
- Source :
-
European Journal of Biochemistry . 9/1/83, Vol. 135 Issue 1, p171-174. 4p. - Publication Year :
- 1983
-
Abstract
- Binding of alkylisocyanides of different bulkiness to the two major components of trout hemolysate is presented. In the case of trout hemoglobin I isocyanide binding is pH-independent, similar to O2 and CO, and the bulkiness of the ligand is related to the endothermicity of ligand binding to the T quaternary state. On the other hand, in trout hemoglobin IV the size of the ligand seems to affect the pH dependence of affinity and cooperativity. A comparison with other ligands, like O2, allows us to hint at possible stereochemical determinants of ligand binding in these two hemoglobins. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEMOGLOBINS
*LIGAND binding (Biochemistry)
*STEREOCHEMISTRY
*BIOCHEMISTRY
Subjects
Details
- Language :
- English
- ISSN :
- 00142956
- Volume :
- 135
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- European Journal of Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 15826423
- Full Text :
- https://doi.org/10.1111/j.1432-1033.1983.tb07633.x