Catastrophic Disruptions in Clinical Trials.

Telephone or digital check-ins, direct to participant drug delivery, and patient-reported end points are all tools that could be used in situations when participants are no longer able to participate in a traditional trial model with scheduled in-person site visits. Keywords: clinical trial protocol; randomized clinical trials EN clinical trial protocol randomized clinical trials 369 371 3 08/02/22 20220802 NES 220802 The clinical research community, like others, has watched the unfolding humanitarian crisis in Ukraine with great concern. One of the most important considerations for a trial during a catastrophe must be the ethics of ongoing trial participation by affected sites and participants. [Extracted from the article]