von Willebrand Factor Is Produced Exclusively by Endothelium, Not Neointima, in Occlusive Vascular Lesions in Both Pulmonary Hypertension and Atherosclerosis.

The same is found in atherosclerosis neointimal lesions (Figure [H and I]), suggesting that this pattern of vWF localization and I VWF/Vwf i transcription is a general characteristic of neointimal lesions in both the systemic and pulmonary vascular beds. Keywords: hypertension, pulmonary; models, animal; vascular remodeling; von Willebrand Factor EN hypertension, pulmonary models, animal vascular remodeling von Willebrand Factor 429 431 3 08/02/22 20220802 NES 220802 vWF (von Willebrand Factor) is a large, secreted, multimeric glycoprotein transcribed by vascular endothelial cells and, to a lesser extent, megakaryocytes throughout the body. [Extracted from the article]