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Cutaneous sporotrichosis in Himachal Pradesh, India.

Authors :
Mahajan, V. K.
Sharma, N. L.
Sharma, R. C.
Gupta, M. L.
Garg, G.
Kanga, A. K.
Source :
Mycoses. Jan2005, Vol. 48 Issue 1, p25-31. 7p.
Publication Year :
2005

Abstract

During the period 1990–2002 in Himachal Pradesh, India, 103 new patients with cutaneous sporotrichosis were detected. Lymphocutaneous and fixed cutaneous varieties were the most common and seen in 49% and 43% respectively. Chronic non-specific inflammation without granuloma formation was seen in 46% skin biopsy specimens, 29% showed acute or chronic inflammation and tuberculoid granuloma formation was seen in 25%. In 32% of casesSporothrix schenckiigrowth was seen on Sabouraud glucose agar. A saturated solution of potassium iodide was used as first-line treatment and in 93% patients healing of lesions occurred in 4–32 weeks (average 8.7 weeks) without significant side-effects. Itraconazole, used in 12 patients, was highly effective in recommended doses. Rapid healing was seen with higher than previously used doses of fluconazole in one patient who also had unusual exacerbation of lesional inflammation with saturated solution of potassium iodide. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09337407
Volume :
48
Issue :
1
Database :
Academic Search Index
Journal :
Mycoses
Publication Type :
Academic Journal
Accession number :
15862499
Full Text :
https://doi.org/10.1111/j.1439-0507.2004.01058.x