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Risk Factors Affecting the Survival Rate of Collagen Meniscal Implant for Partial Meniscal Deficiency: An Analysis of 156 Consecutive Cases at a Mean 10 Years of Follow-up.
- Source :
-
American Journal of Sports Medicine . Sep2022, Vol. 50 Issue 11, p2900-2908. 9p. - Publication Year :
- 2022
-
Abstract
- Background: Collagen meniscal implant (CMI) is a biologic scaffold that can be used to replace meniscus host tissue after partial meniscectomy. The short-term results of this procedure have already been described; however, little is known about risk factors for failure. Purpose: To determine the factors that predict failure of meniscal scaffold implantation in a large series of patients treated at a single institution and to better define the indications for surgery. Study Design: Case-control study; Level of evidence, 3. Methods: The analysis included 186 consecutive patients with a minimum 5-year follow-up who underwent CMI scaffold implantation or combined procedures. Patients' characteristics and details of the surgery were obtained via chart review. Patients with a Lysholm score <65 were considered to have experienced clinical failure. Surgical failure was defined as partial or total scaffold removal. Results: The final analysis included 156 patients (84%) at a mean follow-up of 10.9 ± 4.3 years. The patients' mean age at surgery was 42.0 ± 11.1 years, and the survival rate was 87.8%. Subgroup analysis identified Outerbridge grade 3-4 (Hazard ratio [HR], 3.8; P =.004) and a lateral meniscal implant (HR, 3.2; P =.048) as risk factors for failure. The survival rate was 90.4% for medial implants and 77.4% for lateral implants. An Outerbridge grade 3-4 (HR, 2.8; P <.001) and time from meniscectomy to scaffold >10 years (HR, 2.8; P =.020) were predictive of surgical or clinical failure. Conclusion: CMI for partial meniscal deficiency provided good long-term results, with 87.8% of the implants still in situ at a mean 10.9 years of follow-up. Outerbridge grade 3-4, lateral meniscal implants, and longer time from the meniscectomy to implantation of the CMI were identified as risk factors for clinical and surgical failure. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MENISCUS surgery
*COLLAGEN
*PROSTHETICS
*PATIENT aftercare
*HOMOGRAFTS
*CONFIDENCE intervals
*ARTIFICIAL implants
*CASE-control method
*ACQUISITION of data
*MENISCECTOMY
*TREATMENT effectiveness
*TREATMENT failure
*SURVIVAL rate
*T-test (Statistics)
*MEDICAL records
*CHI-squared test
*KAPLAN-Meier estimator
*DESCRIPTIVE statistics
*DATA analysis software
*LOGISTIC regression analysis
*MENISCUS injuries
*LONGITUDINAL method
SURGICAL complication risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 03635465
- Volume :
- 50
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- American Journal of Sports Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 158866226
- Full Text :
- https://doi.org/10.1177/03635465221112635