Back to Search
Start Over
Total synthesis of 4-((3S,5R)-3,5-dihydroxynonadecyl)phenol.
- Source :
-
Synthetic Communications . 2022, Vol. 52 Issue 17, p1721-1726. 6p. 4 Diagrams. - Publication Year :
- 2022
-
Abstract
- An enantioselective total synthesis of novel gingerol-related compound 4-((3S,5R)-3,5-dihydroxynonadecyl)phenol, an anti-oxidant isolated from the resinous exudates of Chilean desert plants, has been accomplished from a known commercially available 4-(but-3-enyl) phenol by a concise ten-step sequence. In this synthesis, Sharpless asymmetric dihydroxylation, Grignard reaction and Iodine-induced electrophilic cyclization have been applied as key steps. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PHENOL
*GRIGNARD reagents
*DESERT plants
*ANTIOXIDANTS
Subjects
Details
- Language :
- English
- ISSN :
- 00397911
- Volume :
- 52
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Synthetic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 158997959
- Full Text :
- https://doi.org/10.1080/00397911.2022.2112056