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Postnatal and Adult Neurogenesis in Mammals, Including Marsupials.

Authors :
Bartkowska, Katarzyna
Tepper, Beata
Turlejski, Krzysztof
Djavadian, Ruzanna
Source :
Cells (2073-4409). Sep2022, Vol. 11 Issue 17, p2735. 20p.
Publication Year :
2022

Abstract

In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a number of brain structures develop after birth. The exception is the generation of granule cells in the dentate gyrus, olfactory bulb, and cerebellum of eutherian species. The formation of these structures starts during embryogenesis and continues postnatally. In both eutherians and marsupials, neurogenesis continues in the subventricular zone of the lateral ventricle (SVZ) and the dentate gyrus of the hippocampal formation throughout life. The majority of proliferated cells from the SVZ migrate to the olfactory bulb, whereas, in the dentate gyrus, cells reside within this structure after division and differentiation into neurons. A key aim of this review is to evaluate advances in understanding developmental neurogenesis that occurs postnatally in both marsupials and eutherians, with a particular emphasis on the generation of granule cells during the formation of the olfactory bulb, dentate gyrus, and cerebellum. We debate the significance of immature neurons in the piriform cortex of young mammals. We also synthesize the knowledge of adult neurogenesis in the olfactory bulb and the dentate gyrus of marsupials by considering whether adult-born neurons are essential for the functioning of a given area. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20734409
Volume :
11
Issue :
17
Database :
Academic Search Index
Journal :
Cells (2073-4409)
Publication Type :
Academic Journal
Accession number :
159006480
Full Text :
https://doi.org/10.3390/cells11172735