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Microthrombosis as a cause of fulminant myocarditis-like presentation with COVID-19 proven by endomyocardial biopsy.

Authors :
Nakatani, Satoshi
Ohta-Ogo, Keiko
Nishio, Mayu
Amemiya, Kisaki
Sato, Shuho
Sawano, Hirotaka
Hatakeyama, Kinta
Katano, Harutaka
Suzuki, Tadaki
Hirooka, Keiji
Source :
Cardiovascular Pathology. Sep2022, Vol. 60, pN.PAG-N.PAG. 1p.
Publication Year :
2022

Abstract

• Mechanisms of myocardial injury as a complication of COVID-19 have not been well understood. • We experienced a case with cardiogenic shock infected by COVID-19. • With endomyocardial biopsy, there was no sign of typical active myocarditis. • Ischemic changes were found at microvascular level accompanied by microthrombi. • Microvascular thrombotic injury is shown as a cause of fulminant myocarditis-like presentation. Myocardial injury has been reported as a complication of COVID-19. Although several mechanisms have been proposed as its cause, they are mostly based on autopsy studies, We report a 49-year-old male with COVID-19-associated myocardial injury presented like fulminant myocarditis. We performed endomyocardial biopsy on day 2 and we confirmed the presence of microthrombosis histologically. He died on day 5 due to cardiogenic shock. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10548807
Volume :
60
Database :
Academic Search Index
Journal :
Cardiovascular Pathology
Publication Type :
Academic Journal
Accession number :
159076296
Full Text :
https://doi.org/10.1016/j.carpath.2022.107435