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Diethyl(benzamido(diisopropoxyphosphoryl)methyl) phosphonate.

Authors :
López-Francés, Adrián
Palacios, Francisco
Maestro, Aitor
Vicario, Javier
Source :
Molbank. Sep2022, Vol. 2022 Issue 3, pM1424-N.PAG. 6p.
Publication Year :
2022

Abstract

Bisphosphonates are widely used in medicine and related areas, mainly for the treatment of bone diseases, such as osteoporosis. However, their synthesis is usually performed under harsh reaction conditions. In order to overcome this limitation, the present work illustrates a new synthetic route to access the title α-aminobisphosphonate in milder reaction conditions using α-phosphorylated imines as key intermediates. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14228599
Volume :
2022
Issue :
3
Database :
Academic Search Index
Journal :
Molbank
Publication Type :
Academic Journal
Accession number :
159357607
Full Text :
https://doi.org/10.3390/M1424