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Synthesis, Structure, and Antibacterial Activities of Diterpenoid Isosteviol-Derived Alkenyl Ethers.

Authors :
Liu, Cong-Jun
Yu, Zi-Yue
Min, Yu-Tao
Zhang, Jun-Wei
Zhang, Jun
Lu, Zhen-Wei
Yang, Jiong-Peng
Wang, Yu-Fei
Source :
Chemistry of Natural Compounds. Sep2022, Vol. 58 Issue 5, p857-861. 5p.
Publication Year :
2022

Abstract

A series of novel isosteviol-derived alkenyl ethers were synthesized and structurally characterized by IR, NMR, and HR-MS. The tested compounds are more sensitive to Gram-positive bacteria than to Gram-negative bacteria. In particular, compound 5 exhibited better bacteriostatic activity against B. subtilis with a minimum inhibitory concentration of 2.403 mM, whereas compounds 8 and 10 selectively inhibited the S. aureus strain. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00093130
Volume :
58
Issue :
5
Database :
Academic Search Index
Journal :
Chemistry of Natural Compounds
Publication Type :
Academic Journal
Accession number :
159413419
Full Text :
https://doi.org/10.1007/s10600-022-03816-5