Stimulation of Burn Wound Healing in Rats by Nanosecond Repetitive Pulsed Microwave Radiation.

The effect of nanosecond repetitive pulsed microwave radiation (RPMR, 10 GHz, 100 ns pulse duration, 8 Hz pulse repetition rate, 140 and 1500 W/cm2 peak power flux density (pPFD)) on the regeneration of burn wounds in rats in dynamics was investigated. It is established that after 4-fold local irradiation of wounds with intensities of 140 and 1500 W/cm2 at frequency of 8 Hz, wound healing in the control and irradiated groups did not differ significantly (from the 1st day to the 14th day). Statistically significant acceleration of healing of irradiated burn wounds was detected from the 19th day. From the 12th day partial separation of the formed scab was observed. Epithelialization was observed from the 24th day to the 28th day. The effectiveness of RPMR with pPFD of 140 W/cm2 turned out to be higher in comparison with irradiation with pPFD of 1500 W/cm2. [ABSTRACT FROM AUTHOR]