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CROSS-REACTIVITY OF T-CELL 'HELPER' FUNCTION.
- Source :
-
Clinical & Experimental Immunology . Sep1974, Vol. 18 Issue 1, p55-61. 7p. - Publication Year :
- 1974
-
Abstract
- The cross-reactivity of heterologous erythrocytes was measured at the level of the B and the T cell. B cells produced antibody with restricted cross-reactivity as compared with the cross-reactivity of T cells, assayed by their ability to help B cells in a primary anti-sheep erythrocyte immune response. Helper function was maximally elicited with low antigen doses. The data suggest that the T-cell antigen receptors for erythrocyte antigens differ in specificity from those of B cells and that the sensitivity of T cells to antigen may be very great. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ERYTHROCYTES
*IMMUNOGLOBULINS
*T cells
*B cells
*IMMUNE response
*ANTIGENS
Subjects
Details
- Language :
- English
- ISSN :
- 00099104
- Volume :
- 18
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Clinical & Experimental Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 15960918