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SUPERIORITY OF CORPUSCULAR BCG TO SOLUBLE PPD ANTIGEN IN THE LEUCOCYTE MIGRATION ASSAY.
- Source :
-
Clinical & Experimental Immunology . Sep1974, Vol. 18 Issue 1, p149-153. 5p. - Publication Year :
- 1974
-
Abstract
- The recognized trend towards the standardization of the leucocyte migration assay prompted the comparison of efficacy of BCG with soluble purified protein derivative (PPD) antigens in this test. Even low BCG concentrations permit high correlations between in vivo and in vitro responses, whilst PPD doses needed to elicit comparable reactions fall within toxic concentrations. BCG-induced inhibition of leucocyte migration is abolished by the protein synthesis inhibitor, cycloheximide. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LEUCOCYTES
*PROTEINS
*ANTIGENS
*BCG vaccines
*PROTEIN synthesis
*IMMUNITY
Subjects
Details
- Language :
- English
- ISSN :
- 00099104
- Volume :
- 18
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Clinical & Experimental Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 15961211