NEW THERAPEUTIC APPROACHES IN BREAST ANTICANCER TREATMENT USING ARMENIAN HERBAL EXTRACTS.

Armenia has a large diversity of flora, which is not properly explored for the discovery of new biologically active extracts or compounds with promising anticancer therapeutic value. In this work, we investigated the anticancer potential of two Armenian herbal extracts; H. alpestre and R. obtusifolius, against 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats. According to obtained data, H. alpestre and R. obtusifolius methanol extracts can affect the regulation of cancer cell metabolism, which have been reflected in changes of tumors size, weight, numbers, and mortality rate. Therefore, tested two Armenian plant extracts could have high therapeutic potential during breast cancer treatment. [ABSTRACT FROM AUTHOR]