双能 CT 在肝细胞肝癌微血管侵犯中的评估价值.

Objective To investigate the diagnostic value of quantitative parameters of dual-energy CT (DECT) in the microvascular invasion of HCC. Methods Clinicopathological and imaging data of 56 patients, who underwent preoperative DECT for pathologically confirmed HCC were retrospectively analyzed. The iodine densities (ID) of solid part of the lesion, edge of the lesion, within 1 cm of the lesion edge, 1 cm outside the lesion, and abdominal aorta on the same plane in the arterial and venous phases were measured. According to Standardization for Diagnosis and Treatment of Primary Hepatic Carcinoma (2019 edition), all 56 patients were classified as 28 microvascular invasion (MVI) or 28 non-MVI. The parameters of DECT were compared between the two groups. The receiver operating characteristic (ROC) curves were drawn to evaluate the diagnostic efficacy of any statistically significant quantitative parameters in the MVI of HCC. Results There were no significant differences in the ID of outside 1 cm of the lesion in the arterial phase and solid part of the lesion, edge of the lesion, within 1 cm of the lesion in venous phase (P>0.05). There was no significant difference (P> 0.05) between the ID of solid part of the lesion in arterial phase (AUC=0.756) and outside 1 cm edge the lesion in venous phase (0.694). Combined with age, alpha-fetoprotein (AFP), and aspartate aminotransferase (AST), ID of solid part of the lesion in arterial phase and ID of outside 1 cm of the lesion in the venous phase had AUC of 0.926 with sensitivity of 82.14%, and specificity of 96.43%. Conclusion The ID of solid part of the HCC in arterial phase and ID of outside 1 cm of the lesion in the venous phase on DECT can aid preoperative evaluation of HCC microvascular invasion. [ABSTRACT FROM AUTHOR]